2-furoate—CoA ligase
2-furoate-CoA ligase | |||||||||
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Identifiers | |||||||||
EC number | 6.2.1.31 | ||||||||
CAS number | 122320-08-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a 2-furoate—CoA ligase (EC 6.2.1.31) is an enzyme that catalyzes the chemical reaction
- ATP + 2-furoate + CoA AMP + diphosphate + 2-furoyl-CoA
The 3 substrates of this enzyme are ATP, 2-furoate, and CoA, whereas its 3 products are AMP, diphosphate, and 2-furoyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 2-furoate:CoA ligase (AMP-forming). This enzyme is also called 2-furoyl coenzyme A synthetase.
References
- Koenig K, Andreesen JR (1989). "Molybdenum Involvement in Aerobic Degradation of 2-Furoic Acid by Pseudomonas putida Fu1". Appl. Environ. Microbiol. 55 (7): 1829–1834. PMC 202958. PMID 16347977.
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