3-hydroxypimeloyl-CoA dehydrogenase

3-hydroxypimeloyl-CoA dehydrogenase
Identifiers
EC number 1.1.1.259
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 3-hydroxypimeloyl-CoA dehydrogenase (EC 1.1.1.259) is an enzyme that catalyzes the chemical reaction

3-hydroxypimeloyl-CoA + NAD+ 3-oxopimeloyl-CoA + NADH + H+

Thus, the two substrates of this enzyme are 3-hydroxypimeloyl-CoA and NAD+, whereas its 3 products are 3-oxopimeloyl-CoA, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-hydroxypimeloyl-CoA:NAD+ oxidoreductase. This enzyme participates in benzoate degradation via coa ligation.

References


    This article is issued from Wikipedia - version of the 5/25/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.