AP3B2

AP3B2

Identifiers

AP3B2, NAPTB, adaptor related protein complex 3 beta 2 subunit

External IDs

MGI: 1100869 HomoloGene: 55837 GeneCards: AP3B2

Gene ontology
Molecular function	• transporter activity
Cellular component	• cytoplasm • AP-3 adaptor complex • membrane coat • Golgi apparatus • cytoplasmic vesicle • clathrin-coated vesicle membrane • membrane • COPI-coated vesicle • nucleoplasm • axon cytoplasm
Biological process	• anterograde axonal transport • protein transport • anterograde synaptic vesicle transport • intracellular protein transport • vesicle-mediated transport • post-Golgi vesicle-mediated transport • transport
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


8120


11775


ENSG00000103723


ENSMUSG00000062444


Q13367


Q9JME5

RefSeq (mRNA)


NM_001278511 NM_001278512 NM_004644


NM_021492 NM_146192

RefSeq (protein)


NP_001265440.1 NP_001265441.1 NP_004635.2


NP_067467.2

Location (UCSC)

Chr 15: 82.66 – 82.71 Mb

Chr 7: 81.46 – 81.49 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

AP-3 complex subunit beta-2 is a protein that in humans is encoded by the AP3B2 gene.^[3]^[4]^[5]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Newman LS, McKeever MO, Okano HJ, Darnell RB (Oct 1995). "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein". Cell. 82 (5): 773–83. doi:10.1016/0092-8674(95)90474-3. PMID 7671305.
↑ Darnell RB, Furneaux HM, Posner JB (Jun 1991). "Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors". J Neurosci. 11 (5): 1224–30. PMID 1851215.
↑ "Entrez Gene: AP3B2 adaptor-related protein complex 3, beta 2 subunit".

Further reading

Dell'Angelica EC, Ohno H, Ooi CE, et al. (1997). "AP-3: an adaptor-like protein complex with ubiquitous expression.". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonifacino JS (1998). "Association of the AP-3 adaptor complex with clathrin.". Science. 280 (5362): 431–4. doi:10.1126/science.280.5362.431. PMID 9545220.
Lim DS, Kirsch DG, Canman CE, et al. (1998). "ATM binds to beta-adaptin in cytoplasmic vesicles.". Proc. Natl. Acad. Sci. U.S.A. 95 (17): 10146–51. doi:10.1073/pnas.95.17.10146. PMC 21476. PMID 9707615.
Faundez VV, Kelly RB (2000). "The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform.". Mol. Biol. Cell. 11 (8): 2591–604. doi:10.1091/mbc.11.8.2591. PMC 14942. PMID 10930456.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Dubois T, Zemlickova E, Howell S, Aitken A (2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin.". Biochem. Biophys. Res. Commun. 301 (2): 502–8. doi:10.1016/S0006-291X(02)03010-3. PMID 12565890.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Chen C, Zou X, Ji C, et al. (2007). "Characterization of AP3B2_v2, a novel splice variant of human AP3B2.". DNA Seq. 18 (3): 165–8. doi:10.1080/10425170600842121. PMID 17453999.

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