Abietadiene hydroxylase
| Abieta-7,13-diene hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.13.108 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Abieta-7,13-diene hydroxylase (EC 1.14.13.108) is an enzyme with systematic name abieta-7,13-diene,NADPH:oxygen oxidoreductase (18-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction
- abieta-7,13-diene + NADPH + H+ + O2 abieta-7,13-dien-18-ol + NADP+ + H2O
Abietadiene hydroxylase is a heme-thiolate protein (P-450).
References
- ↑ Funk, C.; Croteau, R. (1994). "Diterpenoid resin acid biosynthesis in conifers: characterization of two cytochrome P450-dependent monooxygenases and an aldehyde dehydrogenase involved in abietic acid biosynthesis". Arch. Biochem. Biophys. 308: 258–266. doi:10.1006/abbi.1994.1036. PMID 8311462.
- ↑ Funk, C.; Lewinsohn, E.; Vogel, B.S.; Steele, C.L.; Croteau, R. (1994). "Regulation of oleoresinosis in grand fir (Abies grandis) (coordinate induction of monoterpene and diterpene cyclases and two cytochrome P450-dependent diterpenoid hydroxylases by stem wounding)". Plant Physiol. 106 (3): 999–1005. doi:10.1104/pp.106.3.999. PMC 159624
. PMID 12232380.
External links
- Abieta-7,13-diene hydroxylase at the US National Library of Medicine Medical Subject Headings (MeSH)
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