Acrylyl-CoA reductase (NADH)

Acrylyl-CoA reductase (NADH)
Identifiers
EC number 1.3.1.95
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Acrylyl-CoA reductase (NADH) (EC 1.3.1.95) is an enzyme with systematic name propanoyl-CoA:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

propanoyl-CoA + NAD+ acryloyl-CoA + NADH + H+

The reaction is catalysed in the opposite direction.

References

  1. Hetzel, M.; Brock, M.; Selmer, T.; Pierik, A.J.; Golding, B.T.; Buckel, W. (2003). "Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein". Eur. J. Biochem. 270 (5): 902–910. doi:10.1046/j.1432-1033.2003.03450.x. PMID 12603323.
  2. Kandasamy, V.; Vaidyanathan, H.; Djurdjevic, I.; Jayamani, E.; Ramachandran, K.B.; Buckel, W.; Jayaraman, G.; Ramalingam, S. (2012). "Engineering Escherichia coli with acrylate pathway genes for propionic acid synthesis and its impact on mixed-acid fermentation". Appl. Microbiol. Biotechnol. 97 (3): –. doi:10.1007/s00253-012-4274-y. PMID 22810300.

External links

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