B4GALNT2

B4GALNT2
Identifiers
Aliases B4GALNT2, B4GALT, GALGT2, beta-1,4-N-acetyl-galactosaminyltransferase 2
External IDs MGI: 1342058 HomoloGene: 7329 GeneCards: B4GALNT2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

124872

14422

Ensembl

ENSG00000167080

ENSMUSG00000013418

UniProt

Q8NHY0

Q09199

RefSeq (mRNA)

NM_001159387
NM_001159388
NM_153446

NM_008081

RefSeq (protein)

NP_001152859.1
NP_001152860.1
NP_703147.2

NP_032107.1

Location (UCSC) Chr 17: 49.13 – 49.18 Mb Chr 11: 95.87 – 95.91 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Beta-1,4 N-acetylgalactosaminyltransferase 2 is an enzyme that in humans is encoded by the B4GALNT2 gene.[3][4][5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Dohi T, Yuyama Y, Natori Y, Smith PL, Lowe JB, Oshima M (Sep 1996). "Detection of N-acetylgalactosaminyltransferase mRNA which determines expression of Sda blood group carbohydrate structure in human gastrointestinal mucosa and cancer". International Journal of Cancer. Journal International Du Cancer. 67 (5): 626–31. doi:10.1002/(SICI)1097-0215(19960904)67:5<626::AID-IJC6>3.0.CO;2-W. PMID 8782649.
  4. Montiel MD, Krzewinski-Recchi MA, Delannoy P, Harduin-Lepers A (Jul 2003). "Molecular cloning, gene organization and expression of the human UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase responsible for the biosynthesis of the blood group Sda/Cad antigen: evidence for an unusual extended cytoplasmic domain". The Biochemical Journal. 373 (Pt 2): 369–79. doi:10.1042/BJ20021892. PMC 1223490Freely accessible. PMID 12678917.
  5. "Entrez Gene: B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2".

Further reading

  • Berger EG (Feb 2002). "Ectopic localizations of Golgi glycosyltransferases". Glycobiology. 12 (2): 29R–36R. doi:10.1093/glycob/12.2.29R. PMID 11886838. 
  • Wang HR, Hsieh CY, Twu YC, Yu LC (Jan 2008). "Expression of the human Sd(a) beta-1,4-N-acetylgalactosaminyltransferase II gene is dependent on the promoter methylation status". Glycobiology. 18 (1): 104–13. doi:10.1093/glycob/cwm120. PMID 17965433. 
  • Kawamura YI, Kawashima R, Fukunaga R, Hirai K, Toyama-Sorimachi N, Tokuhara M, Shimizu T, Dohi T (Jul 2005). "Introduction of Sd(a) carbohydrate antigen in gastrointestinal cancer cells eliminates selectin ligands and inhibits metastasis". Cancer Research. 65 (14): 6220–7. doi:10.1158/0008-5472.CAN-05-0639. PMID 16024623. 
  • Lo Presti L, Cabuy E, Chiricolo M, Dall'Olio F (Nov 2003). "Molecular cloning of the human beta1,4 N-acetylgalactosaminyltransferase responsible for the biosynthesis of the Sd(a) histo-blood group antigen: the sequence predicts a very long cytoplasmic domain". Journal of Biochemistry. 134 (5): 675–82. doi:10.1093/jb/mvg192. PMID 14688233. 
  • Piller F, Blanchard D, Huet M, Cartron JP (Jun 1986). "Identification of a alpha-NeuAc-(2----3)-beta-D-galactopyranosyl N-acetyl-beta-D-galactosaminyltransferase in human kidney". Carbohydrate Research. 149 (1): 171–84. doi:10.1016/S0008-6215(00)90376-8. PMID 2425965. 
  • Li PT, Liao CJ, Wu WG, Yu LC, Chu ST (Jun 2011). "Progesterone-regulated B4galnt2 expression is a requirement for embryo implantation in mice". Fertility and Sterility. 95 (7): 2404–9, 2409.e1–3. doi:10.1016/j.fertnstert.2011.03.043. PMID 21481371. 


This article is issued from Wikipedia - version of the 5/19/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.