Geissoschizine methyl ether
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| Names | |
|---|---|
| IUPAC name
Methyl (Z)-2-[(2S,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate | |
| Identifiers | |
| 3D model (Jmol) | Interactive image |
| PubChem | 6443046 |
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| Properties | |
| C22H26N2O3 | |
| Molar mass | 366.46 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Geissoschizine methyl ether is an alkalod contained in the kampo medicine Yokukansan. Geissoschizine methyl ether has an antagonistic effect on 5-HT7 receptors.[1]
References
- ↑ Ueki, T; Nishi, A; Imamura, S; Kanno, H; Mizoguchi, K; Sekiguchi, K; Ikarashi, Y; Kase, Y (2013). "Effects of geissoschizine methyl ether, an indole alkaloid in Uncaria hook, a constituent of yokukansan, on human recombinant serotonin(7) receptor". Cellular and molecular neurobiology. 33 (1): 129–35. doi:10.1007/s10571-012-9878-3. PMID 22968712.
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