Indole-2-monooxygenase
| Indole-2-monooxygenase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.13.137 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Indole-2-monooxygenase (EC 1.14.13.137, BX2 (gene), CYP71C4 (gene)) is an enzyme with systematic name indole,NAD(P)H:oxygen oxidoreductase (2-hydroxylating).[1][2] This enzyme catalyses the following chemical reaction
- indole + NAD(P)H + H+ + O2 indolin-2-one + NAD(P)+ + H2O
Indole-2-monooxygenase is involved in the biosynthesis of protective and allelophatic benzoxazinoids in some plants.
References
- ↑ Frey, M.; Chomet, P.; Glawischnig, E.; Stettner, C.; Grün, S.; Winklmair, A.; Eisenreich, W.; Bacher, A.; Meeley, R.B.; Briggs, S.P.; Simcox, K.; Gierl, A. (1997). "Analysis of a chemical plant defense mechanism in grasses". Science. 277 (5326): 696–699. doi:10.1126/science.277.5326.696. PMID 9235894.
- ↑ Glawischnig, E.; Grun, S.; Frey, M.; Gierl, A. (1999). "Cytochrome P450 monooxygenases of DIBOA biosynthesis: specificity and conservation among grasses". Phytochemistry. 50 (6): 925–930. doi:10.1016/s0031-9422(98)00318-5. PMID 10385992.
External links
- Indole-2-monooxygenase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia - version of the 5/21/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.