Merlin Crossley

Professor Merlin Crossley is an Australian biochemist and the Dean of the Faculty of Science at the University of New South Wales.[1]

Achievements

Crossley completed his doctorate at Oxford University on a Rhodes Scholarship under the supervision of George Brownlee,[2] researching the molecular genetics of Haemophilia B.

During his time at Oxford he discovered two sets of genetic mutations that prevent two key proteins from attaching to the DNA of people with Haemophilia B Leyden, thereby turning off the gene that produces clotting factor IX, which prevents excessive bleeding.[3]

In 2013, more than 20 years after his first discovery, Crossley discovered the third protein that causes Haemophilia B Leyden[4]

Honours and Awards

References

  1. ↑ "Professor Merlin Crossley - Dean of UNSW Science". unsw.edu.au.
  2. ↑ http://www.rhodeshouse.ox.ac.uk/about/rhodes-scholars/rhodes-scholars-complete-list
  3. ↑ "Disruption of a C/EBP binding site in the factor IX promoter is associated with haemophilia B.". Nature. 345 (6274): 444–6. May 1990. doi:10.1038/345444a0. PMID 2342576.
  4. ↑ http://www.biotechlearn.org.nz/news_and_events/news/2013_archive/royal_disease_mystery_solved
  5. ↑ http://nsw.royalsoc.org.au/society/fellows.htm
  6. ↑ http://www.lornegenome.asnevents.com.au/index84bb.html?option=com_content&view=article&id=38&Itemid=29
  7. ↑ http://www.sciencearchive.org.au/awards/awards/gottschalk.html
  8. ↑ http://royalsoc.org.au/awards/edgeworth_david.htm
  9. ↑ https://www.asbmb.org.au/researchmedal.html
  10. ↑ http://www.rhodeshouse.ox.ac.uk/about/rhodes-scholars/rhodes-scholars-complete-list


This article is issued from Wikipedia - version of the 10/1/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.