Nitrosoproline

Nitrosoproline
Names
IUPAC name
1-Nitroso-L-proline
Other names
N-Nitrosoproline; Proline nitric oxide; Proline NO
Identifiers
7519-36-0 YesY
3D model (Jmol) Interactive image
ChemSpider 8594734
PubChem 10419304
Properties
C5H8N2O3
Molar mass 144.13 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Nitrosoproline is a nitroso derivative of the amino acid proline.

The mixture of nitrosoproline with sodium methoxide is known as PROLI/NO (also PROLINO or ProliNO). It is an "ultrafast" nitric oxide donor which is being studied for its research and clinical applications.[1][2]

References

  1. Pluta RM, Rak R, Wink DA, et al. (April 2001). "Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury". Neurosurgery. 48 (4): 884–92; discussion 892–3. doi:10.1227/00006123-200104000-00039. PMID 11322449.
  2. Saavedra JE, Southan GJ, Davies KM, et al. (October 1996). "Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor". J. Med. Chem. 39 (22): 4361–5. doi:10.1021/jm960616s. PMID 8893830.


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