Photoisomerase

A photoisomerase is a protein in the eye that is responsible for isomerizing photopigments.

In order for the eye to function properly, a special chemical called a chromophore is bound to a protein known as an opsin. When a photon strikes the chromophore, it changes shape (isomerizes). It is this change in conformation that the protein detects and eventually leads to vision. Before the chromophore can be reused, it must be converted back to its original conformation. The photoisomerase is the protein responsible for this change. In the mammalian retina, they are believed to be confined to the retinal pigment epithelium.

References

External links

retinal photoisomerase at the US National Library of Medicine Medical Subject Headings (MeSH)
EC 5.2.1.3

Isomerases: geometric (EC 5.2)

5.2.1	FKBP: FKBP1A FKBP1B FKBP2 FKBP3 FKBP5 FKBP6 FKBP8 FKBP9 FKBP10 FKBP52 FKBPL other: Cyclophilin Parvulin Prolyl isomerase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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Photoisomerase

See also

References

External links