Acridone

Acridone

Names
IUPAC name 10H-acridin-9-one
Identifiers
CAS Number	578-95-0 N
3D model (Jmol)	Interactive image Interactive image
ChEBI	CHEBI:50756 Y
ChEMBL	ChEMBL436589 Y
ChemSpider	10188539 Y
ECHA InfoCard	100.008.578
PubChem	2015
InChI InChI=1S/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15) Y Key: FZEYVTFCMJSGMP-UHFFFAOYSA-N Y InChI=1/C13H9NO/c15-13-9-5-1-3-7-11(9)14-12-8-4-2-6-10(12)13/h1-8H,(H,14,15) Key: FZEYVTFCMJSGMP-UHFFFAOYAI
SMILES C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2 O=C1c3ccccc3Nc2ccccc12
Properties
Chemical formula	C13H9NO
Molar mass	195.22 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Acridone is an organic compound based on the acridine skeleton, with a carbonyl group at the 9 position. It may be synthesized by the self-condensation of N-phenylanthranilic acid.^[1]

Derivatives

Acridone constitutes the scaffold of some synthetic compounds with various pharmacological activities. Most recent derivatives still in its development stage, including 3-chloro-6-(2-diethylamino-ethoxy)-10-(2-diethylamino-ethyl)-acridone, have shown some promise as a potential antimalarial drugs.^[2][3]

2-chloroacridone is the precursor used to make clomacran (tranquilizer).

References