HLA-B63


HLA-B (alpha)-β2MG with bound peptide
major histocompatibility complex (human), class I, B63
Alleles	1516, 1517
Structure (See HLA-B)
Shared data
Locus	chr.6 6p21.31

HLA-B63 (B63) is an HLA-B serotype. The serotype identifies certain B*15 gene-allele protein products of HLA-B.^[1]

B63 is one of many split antigens of the broad antigen, B15. B63 identifies the B*1516 and B*1517 allele products.

Serotype

Serotypes B15, B62, B63, B70, B71, B72, B75, B76, B77 recognition of the
HLA B*15 gene products^[2]
B*15	B15	B62	B63	B70	B71	B72	B75	B76	B77	Sample
allele	%	%	%	%	%	%	%	%	%	size (N)
*1516	3		80							816
*1517	2		88							797
Alleles link-out to IMGT/HLA Databease at EBI

**HLA B*1516 frequencies**
		freq
ref.	Population	(%)
^[3]	Ivory Coast Akan Adiopodoume	4.6
	Cameroon Bamileke	3.2
	USA African Americans (3)	1.9
	Italy South Campania	1.6
	United Arab Emerates	1.5
	Brazil	1.4
	Azores S. Maria and S. Miguel	1.3
	Zimbabwe Harare Shona	1.3
	Cameroon Beti	1.1
	Cameroon Yaounde	1.1
	Mali Bandiagara	1.1
	Tunisia Tunis	1.1
	Kenya Nandi	1.0
	Cape Verde SE Islands	0.8
	Kenya	0.7
	Uganda Kampala	0.6
	Brazil Belo Horizonte	0.5
	South African Natal Zulu	0.5
	Sudanese	0.5
	Tunisia	0.5
	Kenya Luo	0.4
	Oman	0.4

**HLA B*1517 frequencies**
		freq
ref.	Population	(%)
^[3]	India Khandesh Pawra	9.0
	South Africa Natal Tamil	3.1
	Saudi Arabia Guraiat and Hail	2.7
	Mexico Zaptotec Oaxaca	2.2
	India North Hindus	1.9
	Bulgaria	1.8
	India North Delhi	1.6
	China Inner Mongolia	1.5
	Georgia Tibilisi Georgians	1.4
	Kenya Luo	1.3
	Cuban Mulatto	1.2
	Brazil Belo Horizonte	1.1
	Cameroon Yaounde	1.1
	Portugal North	1.1
	Tunisia Tunis	1.1
	Kenya Nandi	1.0
	Portugal Centre	1.0
	China Qinghai Hui	0.9
	Israel Ashk. and Non Ashk.i Jews	0.9
	Azores Terceira Island	0.8
	Cape Verde Southeastern Islands	0.8
	France South East	0.8
	India New Delhi	0.8
	Russia Tuva pop 2	0.8
	Sudanese	0.8
	USA African Americans pop3	0.8
	USA Caucasian pop2	0.8
	Brazil	0.7
	Cuban White	0.7
	Thailand	0.7
	USA Philadelphia Caucasians	0.7
	Cameroon Beti	0.6
	Romanian	0.6
	Czech Republic	0.5
	Singapore Thai	0.5
	Spain Eastern Andalusia Gipsy	0.5

↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–369. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
↑ derived from IMGT/HLA
1 2 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)

HLA-B serotypes and allele groups

HLA-B B5 B51 B52 B7 B8 B12 B44 B45 B13 B14 B64 B65 B15 B62 B63 B70 B71 B72 B75 B76 B77 B16 B38 B39 B17 B57 B58 B18 B21 B49 B50 B22 B54 B55 B56 B27 B35 B37 B40 B60 B61 B41 B42 B46 B47 B48 B53 B59 B67 B73 B78 B81 B82 B83

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