HLA-B67




major histocompatibility complex (human), class I, B67
Alleles	B*6701
Structure (See HLA-B)
Symbol(s)	HLA-B
EBI-HLA	B*6701
Locus	chr.6 6p21.31

HLA-B67 (B67) is an HLA-B serotype. The serotype identifies the more common HLA-B*67 gene products.^[1] B67 is region specific recombinant haplotype formed by the gene conversion of B*39, an allele common along the Northwest Pacific Rim (Taiwan, Japan, Korea, Coastal Siberia), and B7, B22, or B27.^[2] (For terminology help see: HLA-serotype tutorial)

Serotype

B67 Serotype recognition of the B*67 allele-group gene products^[3]
B*67	B67	Other	Sample
allele	%	%	size (N)
6701	32	62	81

By allele

**Regions of higher B*6701 frequency**
Japan
Taiwan
Heilongjiang province, China (Harbin city)
Beijing China
Shandong peninsula

**HLA B*6701 frequencies**
		freq
ref.	Population	(%)
^[4]	Osaka Region (Japan)	2.6
^[4]	Hakka (Taiwan)	1.8
^[4]	Japan (5)	1.7
^[4]	Harbin Man (China)	1.7
^[4]	Beijing (China)	1.5
^[4]	Linqu (Shandong, China)	1.1
^[4]	Siraya (Taiwan)	1.0
^[4]	Portugal South	1.0
^[4]	Oold (Mongolia)	1.0
^[4]	American Samoa	1.0
^[4]	Pazeh (Taiwan)	0.9
^[4]	South Korea (3)	0.9
^[4]	N. Korean (Harbin,China)	0.8
^[4]	Arratia Basque (Spain)	0.6
^[4]	Tarialan Khoton (Mongolia)	0.6
^[4]	Shanghai (China)	0.6
^[4]	Natal Zulu (South African)	0.5
^[4]	Yunnan Han (China)	0.5
^[4]	Turkey	0.4
^[4]	Southern Han (China)	0.4
^[4]	Tuva (Russia)	0.3
^[4]	Chinese (Hong Kong, China)	0.1

References

↑ Marsh SG, Albert ED, Bodmer WF, et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
↑ Little AM, Domena JD, Hildebrand WH, et al. (1994). "HLA-B67: a member of the HLA-B16 family that expresses the ME1 epitope". Tissue Antigens. 43 (1): 38–43. doi:10.1111/j.1399-0039.1994.tb02294.x. PMID 7517584.
↑ derived from IMGT/HLA
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in |title= (help)

HLA-B serotypes and allele groups

HLA-B B5 B51 B52 B7 B8 B12 B44 B45 B13 B14 B64 B65 B15 B62 B63 B70 B71 B72 B75 B76 B77 B16 B38 B39 B17 B57 B58 B18 B21 B49 B50 B22 B54 B55 B56 B27 B35 B37 B40 B60 B61 B41 B42 B46 B47 B48 B53 B59 B67 B73 B78 B81 B82 B83

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