Hesperetin

Hesperetin
Names
IUPAC name
(S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
Identifiers
520-33-2 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:28230 YesY
ChEMBL ChEMBL399121 YesY
ChemSpider 65234 YesY
DrugBank DB01094 YesY
ECHA InfoCard 100.007.538
EC Number 208-290-2
KEGG C01709 YesY
PubChem 72281
UNII Q9Q3D557F1 YesY
Properties
C16H14O6
Molar mass 302.28 g·mol−1
Melting point 226–228 °C (439–442 °F; 499–501 K)
Solubility in other solvents Sol. EtOH, alkalis
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Hesperetin is a bioflavonoid and, to be more specific, a flavanone.

Glycosides

A variety of glycosides of hesperetin are known, including:

Metabolism

Hesperidin 6-O-α-L-rhamnosyl-β-D-glucosidase is an enzyme that uses hesperidin and H2O to produce hesperetin and rutinose. It is found in the hyphomycetes species Stilbella fimetaria.

References

  1. Majumdar S.; Srirangam, R. (2009). "Solubility, stability, physicochemical characteristics and in vitro ocular tissue permeability of hesperidin: a natural bioflavonoid". Pharm Res. 26: 1217–1225.
  2. J.S. Chauhan, S.K. Srivastava; M. Sultan, Phytochemistry (1978). "Hesperetin 7-rhamnoside from Cordia oblique". 17 (2): 334. doi:10.1016/S0031-9422(00)94187-6.
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