Small nucleolar RNA SNORD14
| Small nucleolar RNA SNORD14 | |
|---|---|
 Predicted secondary structure and sequence conservation of SNORD14 | |
| Identifiers | |
| Symbol | SNORD14 |
| Alt. Symbols | U14 |
| Rfam | RF00016 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; CD-box |
| Domain(s) | Eukaryota |
| GO | 0006396 0005730 |
| SO | 0000593 |
U14 small nucleolar RNA (U14 snoRNA) is a non-coding RNA required for early cleavages of eukaryotic precursor rRNAs. In yeasts, this molecule possess a stem-loop region (known as the Y-domain) which is essential for function. A similar structure, but with a different consensus sequence, is found in plants, but is absent in vertebrates.[1] In human there are two closely related copies called SNORD14A and SNORD14B that are expressed from the intron of their host gene ribosomal protein Rps13.
References
- ↑ Samarsky, DA; Schneider GS; Fournier MJ (1996). "An essential domain in Saccharomyces cerevisiae U14 snoRNA is absent in vertebrates, but conserved in other yeasts". Nucleic Acids Res. 24 (11): 2059–2066. doi:10.1093/nar/24.11.2059. PMC 145897
. PMID 8668536.
External links
- Page for Small nucleolar RNA SNORD14 at Rfam
- Entry for U14A at snoRNABase
- Entry for SNORD14A in HGNC database
- Entry for U14B at snoRNABase
- Entry for SNORD14B in HGNC database
This article is issued from Wikipedia - version of the 7/24/2014. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.