Thiosulfate sulfurtransferase

This enzyme belongs to the family of transferases, specifically the sulfurtransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is thiosulfate:cyanide sulfurtransferase. Other names in common use include thiosulfate cyanide transsulfurase, thiosulfate thiotransferase, rhodanese, and rhodanase.

Structural studies

As of late 2007, 11 structures have been solved for this class of enzymes, with PDB accession codes 1BOH, 1BOI, 1DP2, 1E0C, 1H4K, 1H4M, 1ORB, 1RHD, 1RHS, 1UAR, and 2ORA.

References

Sorbo BH; Lagerkvist, Ulf; Pesola, Rainer; Virtanen, Artturi I.; Sörensen, Nils Andreas (1953). "Crystalline rhodanese. I. Purification and physicochemical examination". Acta Chem. Scand. 7: 1129–1136. doi:10.3891/acta.chem.scand.07-1129.
Sorbo BH; Lagerkvist, Ulf; Pesola, Rainer; Virtanen, Artturi I.; Sörensen, Nils Andreas (1953). "Crystalline rhodanese. II. The enzyme catalyzed reaction". Acta Chem. Scand. 7: 1137–1145. doi:10.3891/acta.chem.scand.07-1137.
Westley J; Green JR (1959). "Crystalline beef kidney rhodanese". J. Biol. Chem. 234: 2325–6. PMID 13844173.
Thiosulfate Sulfurtransferase at the US National Library of Medicine Medical Subject Headings (MeSH)

Transferases: sulfur-containing group (EC 2.8)

2.8.1: Sulfurtransferases	Thiosulfate sulfurtransferase Rhodanese 3-mercaptopyruvate sulfurtransferase thiosulfate—thiol sulfurtransferase tRNA sulfurtransferase thiosulfate—dithiol sulfurtransferase biotin synthase cysteine desulfurase

2.8.2: Sulfotransferases	Alcohol sulfotransferase Tyrosylprotein sulfotransferase Aryl sulfotransferase

2.8.3: CoA-transferases	Propionate CoA-transferase

2.8.4: Alkylthio	Coenzyme-B sulfoethylthiotransferase

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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