UCK2

UCK2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases UCK2, TSA903, UK, UMPK, uridine-cytidine kinase 2
External IDs MGI: 1931744 HomoloGene: 40850 GeneCards: UCK2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

7371

80914

Ensembl

ENSG00000143179

ENSMUSG00000026558

UniProt

Q9BZX2

Q99PM9

RefSeq (mRNA)

NM_012474

NM_030724

RefSeq (protein)

NP_036606.2

NP_109649.1

Location (UCSC) Chr 1: 165.83 – 165.91 Mb Chr 1: 167.22 – 167.29 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Uridine-cytidine kinase 2 is an enzyme that in humans is encoded by the UCK2 gene.[3]

The protein encoded by this gene catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively. This is the first step in the production of the pyrimidine nucleoside triphosphates required for RNA and DNA synthesis. In addition, an allele of this gene may play a role in mediating nonhumoral immunity to Hemophilus influenzae type B.[3]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles. [§ 1]

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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to PubChem Compound go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to WikiPathways go to article go to article go to article go to article go to article go to article go to article go to article go to article
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FluoropyrimidineActivity_WP1601 go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to PubChem Compound go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to article go to pathway article go to pathway article go to article go to article go to article go to article go to article go to WikiPathways go to article go to article go to article go to article go to article go to article go to article go to article go to article

|{{{bSize}}}px|alt=Fluorouracil (5-FU) Activity edit]]

Fluorouracil (5-FU) Activity edit

  1. The interactive pathway map can be edited at WikiPathways: "FluoropyrimidineActivity_WP1601".

References

Further reading


This article is issued from Wikipedia - version of the 6/29/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.