USP2

USP2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases USP2, UBP41, USP9, ubiquitin specific peptidase 2
External IDs MGI: 1858178 HomoloGene: 3098 GeneCards: USP2
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

9099

53376

Ensembl

ENSG00000036672

ENSMUSG00000032010

UniProt

O75604

O88623

RefSeq (mRNA)

NM_001243759
NM_004205
NM_171997

NM_016808
NM_198091
NM_198092

RefSeq (protein)

NP_001230688.1
NP_004196.4
NP_741994.1

NP_058088.2
NP_932759.1
NP_932760.2

Location (UCSC) Chr 11: 119.36 – 119.38 Mb Chr 9: 44.07 – 44.1 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase 2 is an enzyme that in humans is encoded by the USP2 gene.[3][4]

Ubiquitin (MIM 191339), a highly conserved protein involved in the regulation of intracellular protein breakdown, cell cycle regulation, and stress response, is released from degraded proteins by disassembly of the polyubiquitin chains. The disassembly process is mediated by ubiquitin-specific proteases (USPs). Also see USP1 (MIM 603478).[supplied by OMIM][4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–58. doi:10.1038/nrg1111. PMID 12838346.
  4. 1 2 "Entrez Gene: USP2 ubiquitin specific peptidase 2".

Further reading


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